Oor ons:
A peptide is a chain of amino acids linked by peptide bonds. Peptides are mainly involved in protein regulation, angiogenesis, cell proliferation, melanogenesis, cell migration, and inflammation. Bioactive peptides have been widely used in the cosmetic industry in recent decades. Peptides require low molecular weight (> 500 Da), in order to reduce the diffusion of the peptide between the epidermal layers, high stability and solubility. Over the years, the scientific community has developed a small and stable synthetic peptide fragment that activates collagen production and reduces facial wrinkles and pigmentation. Trifluoroacetyl tripeptide-2 (sequence: TFA-Val-Try-Val-OH) tripeptide synthesis, designed as a matrix metalloproteinase and elastase inhibitor. In vitro studies on the protection of ECM by trifluoro-acetyl tripeptide 2(TT2), the synthesis of proteoglycan in cell-matrix interactions, and the effect on progerin synthesis in mature human normal fibroblasts have been recently identified as a co-inducer of cellular senescence. The results suggest that trifluoroacetyl tripeptide 2 has a broader range of anti-aging properties. This reduces progerin synthesis, increases proteoglycan production, and shrinks collagen, thereby reducing wrinkles and improving tissue stiffness. In addition, its anti-wrinkling, anti-flow hanging and skin tightening effects were evaluated in two in vitro split face studies. Trifluoroacetyl tripeptide 2 has been shown to have progressive effects on wrinkles, tightness, elasticity, and sagging.
Kan trifluoroacetyl tripeptide-2 veroudering vertraag?
Studies het getoon dat sel senesensie nou verwant is aan progerien. Met veroudering versamel presenilien meer en meer in die liggaam, wat lei tot kerndefekte en DNA -skade, wat lei tot 'n verskeidenheid velveroudering. Trifluoroacetyl tripeptide-2 is 'n aktiewe tripeptied van elafien, 'n afgeleide van elastase-remmer. Dit verminder progeriensintese en verbeter die laksheid van die vel, versag en plooie.
Meganisme
1. Inhibeer die sintese van progerien om sellulêre senesensie te vertraag.
2. Bevorder sindekaanse produksie en verleng die sellewe.
3. Inhibeer die aktiwiteit van matriksmetalloproteinases MMP1, MMP3 en MMP9, verminder die afbreek van ekstrasellulêre matriksproteïene en handhaaf hul integriteit.
4. Inhibeer die elastase -aktiwiteit, verminder die afbraak van elastien en maak die vel stywer en meer elasties.
Toepassing
Dit is geskik vir allerlei anti-rimpel en anti-veroudering, stewige herstel, anti-foto-inagneming, na-natale en na-son-liggaamsversorging, ens. Dit word bygevoeg in die laaste fase van die produksie van skoonheidsmiddels
Postyd: 2025-07-02